The Reds have forced two relegation-prone sides to defeats in recent weeks and now the resurgent Hammers are next in line, hoping to receive the same treatment.
The manager suggested there could be substitutions in four games in 11 days, but that wasn't the case with the forced substitution that forced him when Ibrahima Konate missed.
Alisson starts behind four defenders Trent Alexander-Arnold, Joel Matip, Virgil van Dijk, and Andy Robertson.
Fabinho started in midfield despite being suspended for two games due to a yellow card, joined by Jordan Henderson and Curtis Jones.
Mohamed Salah could break into the table for the fourth straight season and will be joined at the top by Diogo Jota and Cody Gakpo.
For options on the bench, the coach again turns to Darwin Nunez and Thiago, as well as Luis Diaz, who is accumulating minutes after a six-month break.
Liverpool is wearing their awesome 'dizzying white' jersey but the good news is that after today we won't have to see them again.
West Ham: Fabianski; Coufal, Aguerd, Zouma, Cresswell; Rice, Paqueta, Soucek; Bowen, Benrahma, Antonio
Liverpool: Alisson, Alexander-Arnold, Matip, Van Dijk, Robertson; Fabinho, Henderson, Jones; Jota, Salah, Gakpo
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